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PhD position at the Max-Delbrueck-Center for Molecular Medicine in Berlin (MyoGrad) (Berlin) PDF Print E-mail
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Saturday, 24 April 2010 20:46

Position:
PhD position at the Max-Delbrück-Center for Molecular Medicine in
Berlin.
The position is available from May 2010.

Affiliated with the MyoGrad International Research Training Group for
Myology (Berlin/Paris).
The project involves the work on animal models for human disease and a
6 month research-visit in Paris.


Job Description:
We are looking for an accomplished, highly motivated, and career
oriented young scientist, preferably with a strong interest in
translational research, cell-biology, and signal transduction.

Experience with either of the following techniques is a plus:
Tissue culture, animal experiments (rat or mouse), experimental or
computational approaches in molecular biology and systems biology.

Prerequisites:
Master degree or diploma. Theoretical and practical knowledge of
molecular and cell biology. Strong interest in biomedical research and
ability to work goal oriented (independently and in the team).
Preferably fluent in English / basic French.

Application (deadline June 1st, 2010):
The application documents should contain a short statement of research
interest, a full CV, and the names and contact information of one,
preferably two references.

Literature:
Peng J, Raddatz K, Labeit S, Granzier H, Gotthardt M. Muscle atrophy
in titin M-line deficient mice. J Muscle Res Cell Motil.
2005;26(6-8):381-8.
Weinert, S., Bergmann, N., Luo, X., Erdmann, B., Gotthardt, M.,
(2006). M line?deficient titin causes cardiac lethality through
impaired maturation of the sarcomere. Journal of Cell Biology 173(4),
559-570.
Radke, M., Peng, J., Wu, Y., McNabb, M., Nelson, O.L., Granzier, H.,
Gotthardt, M. Targeted deletion of Titin?s N2B region leads to
diastolic dysfunction and cardiac atrophy. PNAS 2007; 104(9):3444-9
Peng J., Raddatz, K., Molkentin, J.D., Wu, Y., Labeit, S., Granzier,
H., Gotthardt, M. Cardiac hypertrophy and reduced contractility in
titin kinase deficient hearts. Circulation 2007; 115(6):743-51
Raddatz K, Albrecht D, Hochgräfe F, Hecker M, Gotthardt M. A proteome
map of murine heart and skeletal muscle. Proteomics. 2008
May;8(9):1885-97.
Truncation of titin's elastic PEVK region leads to cardiomyopathy with
diastolic dysfunction. Granzier HL, Radke MH, Peng J, Westermann D,
Nelson OL, Rost K, King NM, Yu Q, Tschöpe C, McNabb M, Larson DF,
Labeit S, Gotthardt M. Circ Res. 2009 Sep 11;105(6):557-64.

About us:
Young research group ?Neuromuscular and Cardiovascular Cell Biology?
that provides an excellent environment at the Max Delbrück Center for
Molecular Medicine (MDC) Berlin-Buch with a combination of basic and
clinical research (the latter in Paris).

For additional information please email me at
This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Or visit us at http://titin.mdc-berlin.de http://www.charite-buch.de/myograd/


Best regards,
Michael Gotthardt

Max Delbrück Center for Molecular Medicine (MDC)
Robert-Rössle Strasse 10
13125 Berlin, Germany
Phone: +49-30 9406 2245
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


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Von:

Michael Gotthardt
This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Max Delbrueck Center for Molecular Medicine (MDC)
Berlin

Ansprechpartner: Michael Gotthardt

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